Physical Sciences
Dr
Donald Daley leads Argenta’s physical sciences, DMPK and IT departments.
Once synthesised, compounds undergo rigorous characterisation,
analysis and structural determinations as required. We have
the capability to perform NMR, MS, IR and single crystal X-ray experiments. High throughput, medium accuracy mass measurements are performed
alongside high throughput LC-MS analysis for structural and
chemical purity determinations.
We utilise the latest equipment, including:
- FractionLynx™ for mass directed auto purification
- MUX LC-MS
- MicroMass Quattro LC-MS-MS
- Perkin Elmer SCIEX API5000
- Varian Unity 400MHz NMR with Zymark autosampler
- Bruker AX300 and AX400MHz NMR
In addition we undertake in vitro PK measurements
and the identification and profiling of metabolites, working
closely with our synthetic chemistry and ADMET
teams.
For more information on our physical sciences capabilities please
contact us. |
PHYSICAL SCIENCES 
