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E argenta@crl.com

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Integrated Drug Discovery

Integrated Drug Discovery

Argenta utilizes a truly integrated approach to small molecule drug discovery, uniting all of the key disciplines required to achieve a programme's goals in a single project team. As an experienced contract drug discovery service provider of choice, Argenta is able to tailor each drug discovery project to flexibly meet the client's specific needs, integrating chemistry, physical sciences, CADD, biology, structural biology, ADMET/PK and disease models as required.

Argenta prides itself in the quality of its staff, at all levels and across all disciplines. Argenta scientists are drawn from a range of pharmaceutical and biotechnology companies and have considerable experience in all phases of drug discovery.

Argenta scientists are well versed in working in a multi-disciplinary environment and place a high value on close and open communication, both within Argenta and with our customers. Our industry-seasoned, multi-functional research teams work closely with our clients' scientists to enhance knowledge, add manpower, shorten time to development candidate identification, and increase the value of their drug discovery programmes.

Research project objectives are defined by the client and translated into research plans by Argenta through several brainstorming sessions between scientists from both organisations. Typically, we will undertake the following projects across the full spectrum of therapeutic areas and on all classes of small molecule druggable targets:

  • Hit identification
  • Hit-to-lead
  • Lead optimisation
  • Assay development and screening
  • Biomarker identification and pharmacodynamic evaluation
  • Backup series provision
  • Drug de-risking, including pharmaceutics
  • Complete drug discovery from target to clinical candidate nomination, including ‘fast follower' programmes

To complement our scientific expertise, Argenta scientists have a thorough awareness of the importance of intellectual property in their work. This includes the ability to establish and evolve patent strategy, understanding the level of information required to patent a novel compound or methodology, performing patent searches and undertaking patent exemplification work.

For more information on our integrated drug discovery capabilities please contact us.